If one is available, read the Medication Guide before your start taking this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Drinking alcohol may cause severe low blood sugar. Discuss this with your health care team. Check with your pharmacist about how to dispose of unused medicine. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. rcep.info atorvastatin
Abteilung Klinische Pharmakologie, Universitat Gottingen, Gottingen, Germany. If you take acarbose with insulin or other diabetes medications, your blood sugar could get too low. Low blood sugar hypoglycemia can occur if you skip a meal, exercise too long, drink alcohol, or are under stress. Sulfonylurea agents or insulin may cause hypoglycemia.
It is recommended that serum transaminase levels be checked every 3 months during the first year of treatment with Acarbose Tablets and periodically thereafter. If elevated transaminases are observed, a reduction in dosage or withdrawal of therapy may be indicated, particularly if the elevations persist. This may not be a complete list of all interactions that may occur. Ask your health care provider if acarbose may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. Hypoglycemia: Because of their mechanism of action, Acarbose Tablets when administered alone should not cause hypoglycemia in the fasted or postprandial state. Sulfonylurea agents or insulin may cause hypoglycemia. Because Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood glucose, it may increase the potential for hypoglycemia. Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, and no increased incidence of hypoglycemia was observed in patients when Acarbose Tablets were added to metformin therapy. Oral glucose dextrose whose absorption is not inhibited by Acarbose Tablets, should be used instead of sucrose cane sugar in the treatment of mild to moderate hypoglycemia. Sucrose, whose hydrolysis to glucose and fructose is inhibited by Acarbose Tablets, is unsuitable for the rapid correction of hypoglycemia.
The following symptoms are uncommon, but if you experience any of them, call your doctor immediately: chest pain, rash. Initial Dosage: The recommended starting dosage of Acarbose Tablets is 25 mg given orally three times daily at the start with the first bite of each main meal. However, some patients may benefit from more gradual dose titration to minimize gastrointestinal side effects. TA and S--TA as well as glibenclamide concentrations were measured with specific analytical methods. RESULTS: There was no clinically relevant change of TA enantiomer pharmacokinetics by glibenclamide or acarbose. Also, glibenclamide pharmacokinetics were not altered by TA to a clinically meaningful extent. Plasma insulin and glucose concentrations did not indicate an interaction between TA and glibenclamide or TA and acarbose. Glibenclamide had the expected effect on insulin and glucose levels independent of comedication. There were only minor and short lasting adverse events with the majority being expected hypoglycaemic symptoms occurring during the treatments with glibenclamide.
This list is not complete. Other drugs may interact with acarbose, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Bloating; diarrhea; gas; stomach pain. The fraction of Acarbose that is absorbed as intact drug is almost completely excreted by the kidneys. When Acarbose was given intravenously, 89% of the dose was recovered in the urine as active drug within 48 hours. In contrast, less than 2% of an oral dose was recovered in the urine as active that is, parent compound and active metabolite drug. This is consistent with the low bioavailability of the parent drug. The plasma elimination half-life of Acarbose activity is approximately 2 hours in healthy volunteers. Loss of Control of Blood Glucose: When diabetic patients are exposed to stress such as fever, trauma, infection, or surgery, a temporary loss of control of blood glucose may occur. At such times, temporary insulin therapy may be necessary. Acarbose treatment resulted in a significant increase in the incidence of renal tumors adenomas and adenocarcinomas and benign Leydig cell tumors. This study was repeated with a similar outcome. Further studies were performed to separate direct carcinogenic effects of Acarbose from indirect effects resulting from the carbohydrate malnutrition induced by the large doses of Acarbose employed in the studies. In one study using Sprague-Dawley rats, Acarbose was mixed with feed but carbohydrate deprivation was prevented by the addition of glucose to the diet. In a 26-month study of Sprague-Dawley rats, Acarbose was administered by daily postprandial gavage so as to avoid the pharmacologic effects of the drug. In both of these studies, the increased incidence of renal tumors found in the original studies did not occur. Acarbose was also given in food and by postprandial gavage in two separate studies in Wistar rats. No increased incidence of renal tumors was found in either of these Wistar rat studies. In two feeding studies of hamsters, with and without glucose supplementation, there was also no evidence of carcinogenicity. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Low blood sugar hypoglycemia can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, confusion, irritability, dizziness, or feeling shaky. Always keep a source of dextrose D-glucose with you in case you have low blood sugar. When taking acarbose, dextrose will work better than cane sugar or table sugar in treating hypoglycemia. Sources of dextrose include honey, dates, raisins, plums, dried prunes, grapes, or glucose tablets. Be sure your family and close friends know how to help you in an emergency. Precose therapy or placebo, titrating to a maximum dose of 100 mg three times daily. Acarbose does not cause low blood sugar hypoglycemia. Acarbose Tablets have been shown to change the bioavailability of digoxin when they are coadministered, which may require digoxin dose adjustment. Acarbose Tablets should be taken three times daily at the start with the first bite of each main meal. Acarbose Tablets should be started at a low dose, with gradual dose escalation as described below, both to reduce gastrointestinal side effects and to permit identification of the minimum dose required for adequate glycemic control of the patient. If the prescribed diet is not observed, the intestinal side effects may be intensified. If strongly distressing symptoms develop in spite of adherence to the diabetic diet prescribed, the doctor must be consulted and the dose temporarily or permanently reduced. Also, the fewer variables in your program, the easier your successes and failures are to track. Keep a recent prescription and your medical history with you. Be prepared for an emergency as you would normally. Make allowances for changing time zones and keep your meal times as close as possible to your usual meal times.
Store acarbose below 77 degrees F 25 degrees C in a tightly sealed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep acarbose out of the reach of children and away from pets. Acarbose is used to treat type 2 diabetes. Acarbose is sometimes used in combination with insulin or other diabetes medications you take by mouth. In initiating treatment for type 2 diabetes mellitus, diet should be emphasized as the primary form of treatment. Caloric restriction and weight loss are essential in the obese diabetic patient. Proper dietary management alone may be effective in controlling blood glucose and symptoms of hyperglycemia. The importance of regular physical activity when appropriate should also be stressed. Avoid taking a digestive enzyme such as pancreatin, amylase, or lipase at the same time you take acarbose. These enzymes can make it harder for your body to absorb acarbose. Products that contain digestive enzymes include Arco-Lase, Cotazym, Donnazyme, Pancrease, Creon, and Ku-Zyme. Do not take more capsules in a day than prescribed by your doctor. Your condition will not improve any faster, and your risk of side effects will increase. Digestive Tract: Gastrointestinal symptoms are the most common reactions to Acarbose Tablets. There is no fixed dosage regimen for the management of diabetes mellitus with Acarbose Tablets or any other pharmacologic agent. Before taking acarbose, tell your doctor if you have liver disease, or any type of stomach or intestinal disorder. Patients Receiving Sulfonylureas or Insulin: Sulfonylurea agents or insulin may cause hypoglycemia. Acarbose Tablets given in combination with a sulfonylurea or insulin may cause a further lowering of blood glucose and may increase the potential for hypoglycemia. If hypoglycemia occurs, appropriate adjustments in the dosage of these agents should be made. Drink plenty of fluids while taking this medication unless your doctor tells you otherwise. You should take the prescribed dose with the FIRST BITE of each main meal. A small dose will be started and your health care provider will gradually increase it as needed. Your health care provider may want you to combine Precose with another type of diabetes pill. Since Precose works differently than the other diabetes pills, it will not interfere with their action. Combined with these pills, Precose may further improve your control. Acarbose has no inhibitory activity against lactase and consequently would not be expected to induce lactose intolerance. plaquenil
Water pulled out of the bloodstream moves into the small intestine. Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition. Because its mechanism of action is different, the effect of Acarbose Tablets to enhance glycemic control is additive to that of sulfonylureas, insulin or metformin when used in combination. In addition, Acarbose Tablets diminish the insulinotropic and weight-increasing effects of sulfonylureas. What are the possible side effects of acarbose Precose? Take at the start with first bite of each main meal; patients should be adhering to a diabetic diet to minimize GI side effects. Adding the a-glucosidase inhibitor, Bayer Corp. If you miss a dose of acarbose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you miss a dose of acarbose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Things like the Chia seeds and Amaranth are great for making beverages which taste good. You may need to do a bit of research on recipes and preparation. Do not use this medication if you are allergic to acarbose, or if you are in a state of diabetic ketoacidosis call your doctor for treatment with insulin. Sorry I couldn't provide a more sound scientific basis, but there are foods around that are not expensive, not genetically engineered, and provided very stable carbohydrate management without having to use a myriad of advanced concoctions. Acarbose did not induce any DNA damage in vitro in the CHO chromosomal aberration assay, bacterial mutagenesis Ames assay, or a DNA binding assay. In vivo, no DNA damage was detected in the dominant lethal test in male mice, or the mouse micronucleus test. In the 59 cases where follow-up was recorded, hepatic abnormalities improved or resolved upon discontinuation of Acarbose Tablets in 55 and were unchanged in two. Cases of fulminant hepatitis with fatal outcome have been reported; the relationship to Acarbose is unclear. lloyds pharmacy clavaseptin review clavaseptin
PrecoseR acarbose tablets to existing therapies for patients with type II diabetes improves long-term blood glucose control, according to final results of the United Kingdom Prospective Diabetes Study. If swallowing is difficult, then the capsule may be opened and the contents mixed in a small amount of liquid or soft food that does not need to be chewed such as room-temperature applesauce. Do not mix the contents of the capsule with alkaline food or liquid such as milk, ice cream, tea. The beans are all very fibrous, complex carbs and release the sugars very slowly - stick to the ribs as they say. If you miss a dose of Glycomet, take as soon as possible. Do not double doses. Symptoms of an early phase happen because food is rapidly "dumping" into the small intestine. Certain drugs tend to produce hyperglycemia and may lead to loss of blood glucose control. These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel-blocking drugs, and isoniazid. When such drugs are administered to a patient receiving Acarbose Tablets, the patient should be closely observed for loss of blood glucose control. When such drugs are withdrawn from patients receiving Acarbose Tablets in combination with sulfonylureas or insulin, patients should be observed closely for any evidence of hypoglycemia. It is a group of symptoms that may result from having part of your removed or from other surgery involving the stomach. The symptoms range from mild to severe and often subside with time. Although you may find dumping syndrome alarming at first, it is not life threatening. You can control it by making changes in what and how you eat. It is important to manage dumping syndrome so you stay well-nourished and don't lose too much weight. Talk to your provider about any symptoms you have and what else you can do. In some cases, or surgery may be needed to help correct the symptoms of dumping syndrome. The small intestine stretches. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs. Do not take other medicines during the time you are taking acarbose unless they have been discussed with your doctor. This especially includes nonprescription medicines such as aspirin, and medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems. The bottom line is today's longetivity is only attributed to advances in medicine that prevent death from early disease or otherwise thwart the natural selection Darwinism process. mail order lotrisone shopping
As a species, we have been eating "modern" food for only about the past 75 years. What happens if I overdose Precose? Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Food and Drug Administration FDA approved the use of acarbose for managing Type 2 diabetes. The brand name for acarbose is Precose. Acarbose blocks the enzymes that digest starches from food. This causes a slower and lower rise of blood sugar through the day. Acarbose is especially effective right after meals. Drink liquids 30 to 45 minutes after meals. ULN, and greater than 3 times the ULN occurred in 14%, 6%, and 3%, respectively, of Acarbose Tablets-treated patients as compared to 7%, 2%, and 1%, respectively, of placebo-treated patients. Although these differences between treatments were statistically significant, these elevations were asymptomatic, reversible, more common in females, and, in general, were not associated with other evidence of liver dysfunction. In addition, these serum transaminase elevations appeared to be dose related. Acarbose Tablets themselves do not cause hypoglycemia even when administered to patients in the fasted state. Sulfonylurea drugs and insulin, however, can lower blood sugar levels enough to cause symptoms or sometimes life-threatening hypoglycemia. Because Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood sugar, it may increase the hypoglycemic potential of these agents. Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, and no increased incidence of hypoglycemia was observed in patients when Acarbose Tablets were added to metformin therapy. The risk of hypoglycemia, its symptoms and treatment, and conditions that predispose to its development should be well understood by patients and responsible family members. Symptoms of high blood sugar hyperglycemia include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your doctor right away. Your dosage may need to be increased or you may need other drugs. It is not known whether this drug passes into milk. Consult your doctor before -feeding. Ask your doctor how to adjust your acarbose dose if needed. Do not change your medication dose or schedule without your doctor's advice. Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide diltiazem Cartia, Cardizem nifedipine Nifedical, Procardia verapamil Calan, Covera, Isoptin, Verelan and others. Take the missed dose as soon as you remember be sure to take it with a meal. If it has been longer than 15 minutes since you started your meal, you may still take acarbose but it may be less effective than taking it with the first bite of the meal. Do not take acarbose between meals, and do not take extra medicine to make up a missed dose.
If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting acarbose. FDA pregnancy category B. Acarbose is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Acarbose does not cause hypoglycemia low blood sugar. However, low blood sugar can occur if you take acarbose with another type of diabetes medicine, delay or miss a meal or snack, exercise more than usual, drink alcohol, or cannot eat because of nausea or vomiting. Symptoms of low blood sugar must be treated before they lead to unconsciousness passing out. Different people may feel different symptoms of low blood sugar. It is important that you learn which symptoms of low blood sugar you usually have so that you can treat it quickly. Laboratory Tests: Therapeutic response to Acarbose Tablets should be monitored by periodic blood glucose tests. Overdose symptoms may include bloating, gas, or stomach discomfort. What happens if I miss a dose Precose? Acarbose does not usually cause low blood sugar. Low blood sugar may be more likely to occur if you skip a meal, exercise heavily, or drink alcohol. It may also be more likely if you take acarbose along with certain medicines for diabetes eg, sulfonylureas, insulin. Tell your doctor right away if you experience symptoms of low blood sugar eg, fast heartbeat, headache, chills, sweating, tremors, increased hunger, vision changes, nervousness, weakness, dizziness, drowsiness, fainting. It is a good idea to carry a reliable source of glucose eg, tablets or gel to treat low blood sugar. This will raise your blood sugar level quickly. Because acarbose prevents the breakdown of table cane sugar, be sure to use glucose dextrose not sugar or fruits, to treat symptoms of low blood sugar. Contact your health care provider if you have any questions. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Do not stop taking any medications without consulting your healthcare provider. Consult your doctor because this may require a change in your treatment plan, medications, or blood sugar testing. Information for Patients: Patients should be told to take Acarbose Tablets orally three times a day at the start with the first bite of each main meal. FDA product labels and may differ in countries outside the USA. Every effort has been made to ensure that the information provided on this page is accurate, up-to-date and complete, but no guarantee is made to that effect. Drugs. buy glipizide vancouver bc
Combine proteins or fats along with fruits or starches. For example, combine fruit with cottage cheese. People with diabetes must take acarbose with the first bite of food at each meal. Acarbose may be used alone as the only diabetes medicine, or with the group of blood-sugar-lowering medicines called sulfonylureas, such as the brand names Diabeta, Glucotrol, and Micronase. Keep all medical appointments. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. If any of these effects persist or worsen, tell your doctor or promptly. In case of overdose, do not eat or drink anything containing carbohydrates for the next 4 to 6 hours. What should I avoid while taking acarbose? PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking acarbose while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking acarbose. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. Diarrhea, gas, upset stomach, constipation, or stomach pain may occur in the first few weeks of treatment as your body adjusts to this medication but usually improve with time. Follow your prescribed diet to help lessen these side effects. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Eat five or six small meals or snacks a day. Its action is quite different from sulfonylureas and metformin. By slowing the digestion of carbohydrates in the small intestine, the blood sugar rise after a meal is lessened. Acarbose works by inhibiting enzymes in the intestine that break carbohydrates down, so glucose levels rise more slowly and the person's own internal production of insulin can more easily respond. Use acarbose as directed by your doctor. Check the label on the medicine for exact dosing instructions. Higher income. Career mobility. isotrexin suppository price in india isotrexin
Some medical conditions may interact with acarbose. Some MEDICINES MAY INTERACT with acarbose. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Do NOT take more than the recommended dose without checking with your doctor. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. Studies on acarbose have been done only in adult patients, and there is no specific information comparing use of acarbose in children with use in other age groups. Glycomet is used to treat type 2 noninsulin-dependent diabetes. Glycomet Glucomin decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. Glycomet Glucomin increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs including any herbal medicines or supplements or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Always consult your doctor or healthcare specialist for medical advice. This list is not complete and other drugs may affect your blood sugar or interact with acarbose. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. cefadroxil
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Do not keep outdated medicine or medicine no longer needed. Inform your doctor if your condition persists or worsens. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. money order levothyroxine online payment
Reclining after eating may help prevent light-headedness. Acarbose is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking acarbose, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. cheapest clozaril buy online shopping
Professor Rury Holman, co-director of the UKPDS, said that patients experienced a very similar reduction in HbA1c over the three-year study period regardless of which existing therapy Precose was added to -- insulin, sulphonylurea, metformin or diet alone. The presence of other medical problems may affect the use of acarbose. Acarbose may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking acarbose. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. The information on this page is not a substitute for the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that a drug or drug combination is safe, effective or appropriate for any given patient. Drugs. clavaseptin
For best results, continue to eat a proper diet, exercise regularly, and check your blood sugar regularly as directed by your doctor. Eight carcinogenicity studies were conducted with Acarbose. Six studies were performed in rats two strains, Sprague-Dawley and Wistar and two studies were performed in hamsters. Teratogenic Effects: Pregnancy Category B. The safety of Acarbose Tablets in pregnant women has not been established.